Description
Zeiss Cirrus 400 OCT — Used Spectral-Domain HD-OCT with GPA and Windows 10
The Zeiss Cirrus 400 HD-OCT is the most affordable entry point into the Cirrus platform — delivering the same proven Zeiss spectral-domain OCT optics, Cirrus normative database, and Guided Progression Analysis (GPA) as the higher-tier Cirrus models at the lowest price in the lineup. This used Zeiss Cirrus 400 runs at 27,000 A-scans per second and has been updated to Windows 10, providing extended software compatibility and a reliable glaucoma and retina imaging platform for practices adding OCT for the first time or expanding to a second imaging lane.
Clinical evidence published in the National Library of Medicine confirms that the Zeiss Cirrus normative database — built into every Cirrus HD-OCT including the 400 — provides statistically validated RNFL thickness comparisons that are foundational to modern glaucoma progression monitoring and among the most cited reference datasets in published glaucoma research.
What’s Included
- Zeiss Cirrus HD-OCT 400 main unit
- Integrated workstation with Cirrus software (Windows 10)
- Patient chin and forehead rest assembly
- Monitor, keyboard, and mouse
- Power and data cables
- 90-day Digital Eye Center warranty
Why Practices Choose the Zeiss Cirrus 400
- Most affordable Cirrus entry point — same Zeiss spectral-domain optics and Cirrus software platform as the 4000 and 5000 at the lowest price in the lineup; the most cost-effective way to access the Cirrus normative database
- 27,000 A-scans per second — spectral-domain OCT speed delivers high-resolution macular and optic disc imaging for the full Cirrus protocol suite with minimal motion artifact
- Guided Progression Analysis (GPA) — serial RNFL comparison with statistical significance flags; the documentation standard for glaucoma change detection across all Cirrus models
- Macular Cube 512×128 — dense macular sampling for retinal thickness mapping, AMD drusen analysis, and diabetic macular edema monitoring
- Optic Disc Cube 200×200 — full optic nerve head quantification with rim area, C/D ratio, and RNFL thickness map
- Cirrus normative database — age-stratified RNFL and macular thickness normative values shared across all Cirrus models; data consistent with any Cirrus 4000 or 5000 in the practice
- Windows 10 updated — extended operating system life and continued software support; improved stability over older Windows XP/7 versions
Clinical Applications
- Glaucoma screening and progression monitoring — GPA-powered RNFL analysis with the Cirrus normative database; meets documentation requirements for glaucoma suspect management and co-management reporting
- Macular disease management — retinal thickness maps for age-related macular degeneration, diabetic macular edema, epiretinal membrane, and central serous retinopathy
- Optic nerve head documentation — quantified C/D ratio, rim area, and RNFL deviation map for ocular hypertension and glaucoma monitoring
- First OCT for new practices — the Cirrus platform is the most widely used OCT in the US; the 400 lets practices establish Cirrus-based workflows at the entry-level price point
- Second imaging lane overflow — identical workflow to Cirrus 4000 and 5000; staff trained on any Cirrus model can use the 400 immediately without retraining
Who This Is For
- Practices adding OCT for the first time — the Cirrus 400 delivers proven platform reliability and the most widely referenced normative database in glaucoma at the lowest acquisition cost
- Optometry practices entering glaucoma co-management — GPA and the Cirrus normative database are accepted across major co-management frameworks; the 400 provides everything needed for RNFL-based documentation
- Practices upgrading from time-domain OCT — the Cirrus 400 provides a meaningful resolution, speed, and analysis upgrade from Stratus OCT and similar time-domain instruments
- High-volume practices adding a second OCT lane — same software workflow as the Cirrus 4000 and 5000; identical normative comparisons across instruments in the practice
- Budget-conscious buyers who want Cirrus reliability — the 400 shares the same Zeiss imaging architecture as the higher-tier Cirrus models at roughly $4,000 less than the Cirrus 4000
Technical Specifications
| Spec | Detail |
| Manufacturer | Carl Zeiss Meditec |
| Model | Cirrus HD-OCT 400 |
| Technology | Spectral-domain OCT (SD-OCT) |
| Scan Speed | 27,000 A-scans/second |
| Axial Resolution | 5 µm (tissue) |
| Scan Width | 6 mm × 6 mm |
| Protocols | Macular Cube 512×128, Optic Disc Cube 200×200, HD 5-Line Raster |
| Analysis Tools | GPA, RNFL thickness maps, optic disc parameters, macular thickness maps |
| Operating System | Windows 10 (updated) |
| OCTA | Not included |
| Condition | Used |
| Warranty | 90 days |
Condition & Warranty
Used. This Zeiss Cirrus 400 has been inspected and verified operational by a certified ophthalmic equipment technician. Covered by a 90-day warranty on parts and workmanship.
Compare Zeiss Cirrus HD-OCT Models
| Model | Speed | GPA | Condition | Price |
| Cirrus 500 | 68K A-scans/s | Yes | Refurbished | $22,325 |
| Cirrus 4000 | 27K A-scans/s | Yes | Used | $15,400 |
| Cirrus 400 (this unit) | 27K A-scans/s | Yes | Used | $11,000 |
Also consider the Optovue RTVue-100 OCT with Anterior Module — refurbished SD-OCT with anterior segment imaging at $12,500.
Questions about the Zeiss Cirrus 400? Contact us — we’ll confirm the software version and provide sample scan images on request.











